The treatment of soil infested with the human whipworm, Trichuris trichiura

Patent Human Infections with the Whipworm, Trichuris trichiura, Are Not Associated with Alterations in the Faecal Microbiota

BACKGROUND The soil-transmitted helminth (STH), Trichuris trichiura colonises the human large intestine where it may modify inflammatory responses, an effect possibly mediated through alterations in the intestinal microbiota. We hypothesised that patent T. trichiura infections would be associated with altered faecal microbiota and that anthelmintic treatment would induce a microbiota resembling...

Two quantitative trait loci influence whipworm (Trichuris trichiura) infection in a Nepalese population.

BACKGROUND Whipworm (Trichuris trichiura) infection is a soil-transmitted helminth infection that affects >1 billion people. It is a serious public health problem in many developing countries and can result in deficits in growth and cognitive development. In a follow-up study of significant heritability for whipworm infection, we conducted the first genome scan for quantitative trait loci (QTL)...

The public health significance of Trichuris trichiura.

An estimated 1049 million persons harbour T. trichiura, including 114 million preschool-age children and 233 million school-age children. The prevalence of T. trichiura is high and may reach 95% in children in many parts of the world where protein energy malnutrition and anaemias are also prevalent and access to medical care and educational opportunities is often limited. The Trichuris dysenter...

An apparent case of human infection with the whipworm of dogs, Trichuris vulpis (Froelich, 1789).

Difetarsone in outpatient treatment of Trichuris trichiura infestation.

Dysentery due to infestation with the whipworm, Trichuris trichiura, is common among underprivileged children living in Cape Town. Chronic blood loss and a diet deficient in iron leads to profound anaemia and it is not unusual for young children with this infestation to present in cardiac failure. While temporary correction of anaemia and treatment ofiron deficiency are readily achieved, eradic...